Suplasyn® is composed of Sterile Sodium Hyaluronate solution 10 mg/ml. Suplasyn® and Suplasyn® 1-Shot are indicated in the symptomatic treatment of osteoarthritis. Suplasyn® m.d. is indicated as a viscoelastic supplement for small synovial joints1. Suplasyn® is administered intra-articularly into the synovial space of affected joint (e.g. knee, hip, toe, ankle, thumb).

In osteoarthritis, hyaluronic acid present in the liquid inside healthy joints (synovial fluid) is reduced, and this loss changes the viscosity and elasticity properties of the fluid that affects its naturally cushioning and lubricating properties. All these result in joint pain, stiffness and possibly more susceptibility to tissue damage. 2,3,4

The introduction of Suplasyn® into the synovial space will assist in the normalization of the joint following arthrocentesis. 3

Suplasyn® has been shown to be beneficial in osteoarthritis for the management of pain and improvement in physical function of joints. 1

  1. Suplasyn® Patient leaflets
  2. Blanch Rubio J et al. Springer Experience & Drug Evidence. 2012.
  3. Gydek A, et al. Przegl Lek.2011;68(6):307-10.
  4. Necas L. et al. Veterinarni Medicina, 53, 2008 (8): 397–411 J.
  5. Petrella RJ et al. J Rheumatol. 2006 May;33(5):951-6.
Your doctor will administer Suplasyn® intra-articularly into the synovial space of your affected joint. Each administration of Suplasyn® takes only a few minutes and can be administered by a physician.

Routinely once inside the medical consult, you will be asked to sit or lie in a comfortable position. Your doctor will likely apply a numbing agent before your Suplasyn®. You may feel some discomfort during the injection, but this normally disappears quickly.

Following the injection, some patients may experience a mild local reaction like pain, heat, redness and swelling. 4

If these symptoms occur, rest the affected joint and apply ice locally. For most of the patients, symptoms subside within days.

If you feel that symptoms are severe or if they persist, you should consult your doctor.

Discontinue use if adverse reactions are experienced.

For further information, please refer to the patient leaflet.

4. Necas L. et al. Veterinarni Medicina, 53, 2008 (8): 397–411 J.

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