Cystistat® FOR PATIENT

Cystistat^® is a medical device for the temporary replacement of the deficient glycosaminoglycan (GAG) layer in the bladder.

Cystistat^® is a medical device for the temporary replacement of the deficient glycosaminoglycan (GAG) layer in the bladder. Cystistat^® is a sterile sodium hyaluronate solution containing 40 mg/50 mL sodium hyaluronate. The GAG layer is deficient in cystitis; Cystistat^® is instilled into the bladder to alleviate symptoms associated with cystitis.

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Patient Leaflet

Advice sheet

WHAT IS CYSTITIS?

Cystitis is the medical term for inflammation of the bladder.

In recent years there has been an increasing number

In recent years there has been an increasing number of studies advocating a significant role of glycosaminoglycans (GAGs) disorder in the pathogenesis of chronic bladder diseases.3,4

Intact GAG layer

The bladder is protected by a mucous layer known as the GAG layer and is thought to protect the underlying urothelium from irritants contained in urine.3

Damaged GAG layer

There is evidence that the GAG layer of the bladder is deficient in cystitis. This deficiency contributes to the clinical symptoms in the diseases such as interstitial cystitis, cystitis caused by infections, trauma, urolithiasis, urinary retention, neoplasia and radiation induced cystitis.5

50 % of the patients were free of bladder symptom after primary therapy of Cystistat^® without any further therapy during the 5 year follow-up¹.

( Engelhardt PF, Morakis N, Daha LK, et al. Long-term results of intravesical hyaluronan therapy in bladder pain syndrome/interstitial cystitis. Int Urogynecol J. 2011;22(4):401-5)

International Journal of Urogynecology

Cystistat® for Patient